解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A 73-year-old woman showed marked exophytic growth of a tumor (25 × 23 × 14 mm) of the nipple over a period of 2 months. Histologically, numerous tumor nodules with no apparent keratinization were observed in the exophytic lesion. The tumor cells also showed little invasion to the dermis and no metastasis to the axill...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-010-0520-5
更新日期:2011-09-01 00:00:00
abstract::Ameloblastoma (AB), which is the most common odontogenic tumor, may originate from the dental lamina remnants. The expression of CD56, which is a transmembrane molecule, is associated with neuroectodermal differentiation of the embryonal cells. The aim of this study was to evaluate the expression of CD56 in AB, in com...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-010-0510-7
更新日期:2011-06-01 00:00:00
abstract::Desquamation in the mammalian skin is a well-balanced process of producing corneocytes and shedding them from the surface of the skin. The corneodesmosome, which is a modified desmosome, is the main adhesive structure in the cornified cell layer. The major extracellular constituents of corneodesmosomes are desmoglein ...
journal_title:Medical molecular morphology
pub_type: 杂志文章,评审
doi:10.1007/s00795-010-0513-4
更新日期:2011-03-01 00:00:00
abstract::Acquired cystic disease (ACD)-associated renal cell carcinoma (RCC) has been recently described. To date, there are no reports on genetic findings of G-band karyotype of ACD-associated RCC. In this article, we report the first report of G-band karyotype of ACD-associated RCC. A 66-year-old Japanese man was found to ha...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-009-0465-8
更新日期:2010-12-01 00:00:00
abstract::In the human placenta, embryo-derived trophoblasts aggressively invade maternal spiral arteries and transform the arteries to low-resistance large-caliber vessels. This process, which ensures adequate placental perfusion, is called maternal vascular remodeling. Histological examination showed deposition of maternal pl...
journal_title:Medical molecular morphology
pub_type: 杂志文章,评审
doi:10.1007/s00795-010-0508-1
更新日期:2010-09-01 00:00:00
abstract::We examined the effects of low protein intake on the development of the remaining kidney in subtotally (5/6) nephrectomized immature rats. Three-week-old rats were kept on a diet containing either 12% protein (Lp rats) or 18% protein (Np rats) for 4 or 8 weeks after subtotal nephrectomy (SUNx). In Western blot analysi...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-009-0485-4
更新日期:2010-06-01 00:00:00
abstract::Aquaporins (AQPs) are key regulators of water channels across the cell cytoplasm. Little is known about AQP localization and changes in the hepatic microvascular system. This study aimed to clarify the localization of AQP-1 in the microvessels in normal and cirrhotic rat liver. To establish a rat cirrhosis model, thio...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-009-0475-6
更新日期:2010-03-01 00:00:00
abstract::IgG4-related disease has been recently described. This disease occurs in various anatomic locations including pancreas, biliary tract, liver, retroperitoneum, kidney, breast, lung, thyroid gland, prostate, salivary gland, lacrimal gland, and lymph node. In this article, we report the first case of IgG4-related disease...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-008-0425-8
更新日期:2009-12-01 00:00:00
abstract::In the process of ovary sexual maturation, most immature ovarian follicles degrade into atretic follicles accompanied by apoptosis in granulosa cells. Macrophages can recognize apoptotic cells through specific binding with phosphatidylserine (PS), exposed on the surface of apoptotic cells, which is mediated by milk-fa...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-009-0452-0
更新日期:2009-09-01 00:00:00
abstract::To evaluate the peculiar "inside-out" pattern in micropapillary (MP) carcinoma, we investigated the usefulness of KL-6 antibody in the assessment of the MP pattern of cancers, in comparison with antibodies to epithelial membrane antigen (EMA), MUC1 (CD227), and CD 10. Immunohistochemical investigation was performed on...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-009-0450-2
更新日期:2009-06-01 00:00:00
abstract::The Tian-Long (TL) compound is a water-soluble extract of six Chinese medicinal herbs. To explore its antitumor properties and the mechanism for activity in gynecological malignancies, the present studies were carried out using Ishikawa cells derived from uterine endometrial adenocarcinoma. Morphologically, cell death...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-008-0424-9
更新日期:2009-03-01 00:00:00
abstract::A few studies of the morphogenesis of human herpesvirus (HHV) 6 type A and B (HHV-6A, -6B) have been performed using neurogenic, lymphoid, or epithelial cells. When human MT-4 T-lymphotropic virus type I (HTLV-I)-producing lymphoid cells were coinfected with HHV-6B in vitro, viral-specific proteins were clearly detect...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-008-0413-z
更新日期:2008-12-01 00:00:00
abstract::Brush cells (BCs) are relatively rare cells that are sparsely distributed throughout the mammalian digestive and respiratory systems. BCs have been identified in the rodent large intestine, but these cells have not been characterized by immunocytochemistry or electron microscopy. We previously demonstrated that rat bi...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-008-0412-0
更新日期:2008-09-01 00:00:00
abstract::Almost every cell in our organism releases proteins and other biological substances using a fundamental cellular process known as constitutive exocytosis. In contrast, in exocrine and endocrine glands, the cells are inherent in an additional and more refined release mechanism directly tuned by extracellular signals. T...
journal_title:Medical molecular morphology
pub_type: 杂志文章,评审
doi:10.1007/s00795-008-0400-4
更新日期:2008-06-01 00:00:00
abstract::Our study was designed to clarify the role of antioxidant enzymes in the rat von Ebner gland during acute nickel toxicity. After treatment with nickel acetate, we monitored ultrastructural alterations in acinar and ductal cells, immunohistochemical staining for glutathione peroxidase (GPx) and glutathione S-transferas...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-007-0386-3
更新日期:2008-03-01 00:00:00
abstract::We studied the distribution of myofibroblasts in the stroma of normal seminal vesicles. Twelve normal seminal vesicles obtained by surgery on the diagnosis of some diseases were selected, and we evaluated the distribution of myofibroblasts in the seminal vesicles using immunohistochemical and electron and immunoelectr...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-007-0378-3
更新日期:2007-12-01 00:00:00
abstract::A 59-year-old Japanese man presented with a giant submucosal tumor with ulceration during follow-up of duodenal ulcer. Pancreaticoduodenectomy was undertaken, and subsequent histological examination of the tumor disclosed anaplastic carcinoma of the pancreas head. The carcinoma components contained adenocarcinoma and ...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-006-0349-0
更新日期:2007-09-01 00:00:00
abstract::Malignant müllerian mixed tumors (MMMTs) of the fallopian tube are very rare neoplasms, and we present such a case with unusual findings here. A 57-year-old Japanese woman, after she received a medical checkup, underwent salpingo-oophorectomy on the suspicion of ovarian cancer. At the time of operation, the main tumor...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-006-0327-6
更新日期:2007-03-01 00:00:00
abstract::Detachment of mesothelial cells is an early step in adhesion of the human pleura. To elucidate this process, we used adhesion molecules as the targets of primary antibody and performed immunohistochemical staining of the mesothelial cells that cover the surface of the sites of pleural adhesion and the macrophages that...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-006-0340-9
更新日期:2006-12-01 00:00:00
abstract::Progression of liver fibrosis has been linked with injuries associated with hypoxia and neovascularization. Neovascularization consists of angiogenesis and vasculogenesis, representing formation of blood vessels by differentiation of endothelial progenitor cells (EPCs). We investigated antifibrogenic and regenerative ...
journal_title:Medical molecular morphology
pub_type: 杂志文章,评审
doi:10.1007/s00795-006-0311-1
更新日期:2006-03-01 00:00:00
abstract::The normal mammary gland can be roughly divided into the large duct close to the nipple and the terminal duct located within the lobulus. Both the large duct and the terminal duct are composed of epithelial cells and myoepithelial cells. The epithelial cells can be divided into light and dark cells using electron dens...
journal_title:Medical molecular morphology
pub_type: 杂志文章,评审
doi:10.1007/s00795-005-0300-9
更新日期:2005-12-01 00:00:00
abstract::Hirschsprung's disease is a congenital aganglionic neural disorder of the segmental distal intestine characterized by unsettled pathogenesis. The relationship between Hirschsprung's disease and pacemaker cells (PMC), which almost corresponds to that of the interstitial cells of Cajal (ICC), was morphologically observe...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-004-0283-y
更新日期:2005-06-01 00:00:00
abstract::In the present study, we investigated the changes in the localization of the glucose transporter GLUT2 and the fructose transporter GLUT5 in small intestinal absorptive cells during postnatal development, especially during the weaning period, using immunohistochemistry and confocal laser scanning microscopy. In the je...
journal_title:Medical molecular morphology
pub_type: 杂志文章
doi:10.1007/s00795-004-0275-y
更新日期:2005-03-01 00:00:00